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Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days for obtaining the report for the Estrogen Receptor (ER) Test Immunohistochemistry is typically 5-7 business days. However, this duration may vary depending on the laboratory and testing facility.

What are the prerequisites for the test Estrogen Receptor (ER) Test Immunohistochemistry

  • Tissue sample (biopsy or surgical specimen) fixed in 10% neutral buffered formalin
  • Paraffin-embedded tissue blocks
  • Microtome for sectioning tissue
  • Slides for mounting tissue sections
  • Reagents for deparaffinization and antigen retrieval
  • Primary antibody against Estrogen Receptor (ER)
  • Secondary antibody conjugated with a detection system (e.g. HRP or AP)
  • Chromogen substrate for visualization (e.g. DAB or BCIP/NBT)
  • Counterstain (e.g. hematoxylin)
  • Mounting medium for preserving the stained tissue sections

What are the measure values for the test Estrogen Receptor (ER) Test Immunohistochemistry

Measure Value
Positive >1% of tumor cells staining
Negative ≤1% of tumor cells staining

What does this test Estrogen Receptor (ER) Test Immunohistochemistry identify?

Estrogen Receptor (ER) Test Immunohistochemistry

The Estrogen Receptor (ER) Test Immunohistochemistry is used to identify the presence and distribution of estrogen receptors in a tissue sample. Estrogen receptors are proteins that are found on the surface of cells and play a key role in responding to estrogen hormones.

By conducting this test, healthcare providers can determine whether the tissue sample is ER-positive or ER-negative. An ER-positive result indicates that the tissue has estrogen receptors and may respond to hormonal therapies targeting these receptors. This information is particularly important in the diagnosis and treatment of hormone receptor-positive breast cancer.

Why is this test Estrogen Receptor (ER) Test Immunohistochemistry taken?

  • Estrogen Receptor (ER) Test Immunohistochemistry:

    • The Estrogen Receptor (ER) Test Immunohistochemistry is taken to determine the presence of estrogen receptors in breast cancer cells. This test helps in predicting the response of the cancer cells to hormonal therapy. Estrogen receptors are proteins found on the surface of breast cancer cells that bind to estrogen hormones. If the cancer cells have estrogen receptors, they may respond well to treatments that block estrogen production or interfere with the action of estrogen.

Popular FAQs on Test

The Estrogen Receptor (ER) Test Immunohistochemistry is a test used to determine the presence of estrogen receptors in cancer cells. Estrogen receptors help cancer cells grow in response to estrogen. This test is commonly used in breast cancer patients to help determine the best treatment options.
The ER Test Immunohistochemistry is important because it helps doctors determine the most effective treatment for patients with estrogen receptor-positive breast cancer. Patients with ER-positive tumors may benefit from hormone therapy, which can block the effects of estrogen on cancer cells.
During the ER Test Immunohistochemistry, a small sample of tissue is taken from the tumor and stained with special antibodies that can detect estrogen receptors. The tissue sample is then examined under a microscope to determine the presence and amount of estrogen receptors in the cancer cells.
The results of the ER Test Immunohistochemistry can help determine the likelihood of a patient responding to hormone therapy. If the cancer cells have a high level of estrogen receptors, hormone therapy may be an effective treatment option. On the other hand, if the cancer cells do not have estrogen receptors, other treatment options may be considered.
The ER Test Immunohistochemistry is a minimally invasive procedure and generally safe. However, there is a small risk of bleeding, infection, or damage to surrounding tissues. Some patients may experience discomfort or bruising at the biopsy site. It is important to discuss any concerns with your healthcare provider.

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