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Parameters

Reports Within:

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Requisites
Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days to obtain the report for the NTRK1/2/3 Gene Rearrangement Test by FISH is typically 14 business days.

What are the prerequisites for the test NTRK1/2/3 Gene Rearrangement Test by FISH

  • Specimen Type: Formalin-fixed, paraffin-embedded (FFPE) tissue block or slides
  • Specimen Size: Minimum of 5 unstained slides or 1 FFPE tissue block
  • Specimen Requirements: Adequate tumor content for analysis
  • Turnaround Time: 7-10 days

What are the measure values for the test NTRK1/2/3 Gene Rearrangement Test by FISH

  • NTRK1 Gene Rearrangement Test: Positive or Negative
  • NTRK2 Gene Rearrangement Test: Positive or Negative
  • NTRK3 Gene Rearrangement Test: Positive or Negative

What does this test NTRK1/2/3 Gene Rearrangement Test by FISH identify?

  • This test identifies rearrangements involving the NTRK1, NTRK2, and NTRK3 genes.
  • Rearrangements in these genes can result in fusion proteins that drive the growth of certain types of cancer.
  • Fluorescence in situ hybridization (FISH) is used to detect these rearrangements by labeling specific DNA sequences with fluorescent probes.
  • Identifying NTRK gene rearrangements can help guide targeted therapy options for patients with cancers that harbor these alterations.

Why is this test NTRK1/2/3 Gene Rearrangement Test by FISH taken?

  • The NTRK1/2/3 Gene Rearrangement Test by FISH is taken to detect rearrangements involving the NTRK genes, which can lead to the formation of oncogenic fusion proteins.
  • These gene rearrangements are known to drive the growth of certain types of cancer, such as non-small cell lung cancer, colorectal cancer, and various types of sarcomas.
  • The test helps in identifying patients who may benefit from targeted therapy with NTRK inhibitors, such as larotrectinib or entrectinib.
  • It is also used to guide treatment decisions and monitor the response to targeted therapy in patients with NTRK gene rearrangements.
  • Overall, the NTRK1/2/3 Gene Rearrangement Test by FISH plays a crucial role in personalized medicine and improving outcomes for cancer patients with NTRK gene alterations.

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