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Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days for obtaining the report for the test Chronic Lymphocytic Leukemia (CLL) Comprehensive Diagnostic Panel is typically 7-10 business days. However, this timeframe may vary depending on the laboratory and specific circumstances.

What are the prerequisites for the test Chronic Lymphocytic Leukemia (CLL) Comprehensive Diagnostic Panel

  • Complete Blood Count (CBC) with differential
  • Peripheral blood smear examination
  • Flow cytometry immunophenotyping
  • Fluorescence in situ hybridization (FISH) for common CLL-associated chromosomal abnormalities
  • PCR analysis for immunoglobulin heavy chain variable region gene (IGHV) mutation status
  • Bone marrow biopsy and aspirate with immunohistochemistry and cytogenetic analysis

What are the measure values for the test Chronic Lymphocytic Leukemia (CLL) Comprehensive Diagnostic Panel

Test Name Measure Values
White Blood Cell Count 4.5 - 11.0 x10^3/μL
Hemoglobin 13.5 - 17.5 g/dL
Platelet Count 150 - 450 x10^3/μL
Lymphocytes 20 - 40 % of total WBC
CD19 Expression on B-Lymphocytes Positive
CD5 Expression on B-Lymphocytes Positive

What does this test Chronic Lymphocytic Leukemia (CLL) Comprehensive Diagnostic Panel identify?

  • Chronic Lymphocytic Leukemia (CLL) Comprehensive Diagnostic Panel includes tests to identify:
    • Complete Blood Count (CBC): This test measures the number of red blood cells, white blood cells, and platelets in the blood. In CLL, there may be an increase in lymphocytes, a type of white blood cell.
    • Flow Cytometry: This test analyzes the markers on the surface of the blood cells to determine if there is an abnormal population of lymphocytes that are characteristic of CLL.
    • Immunoglobulin Testing: This test measures the levels of immunoglobulins (antibodies) in the blood, which can be abnormal in CLL patients.
    • FISH (Fluorescence In Situ Hybridization) Analysis: This test detects specific genetic abnormalities, such as deletions or translocations, that are commonly found in CLL patients.
    • Molecular Testing: This test looks for mutations in genes such as TP53 or NOTCH1 that may affect the prognosis and treatment options for CLL.

Why is this test Chronic Lymphocytic Leukemia (CLL) Comprehensive Diagnostic Panel taken?

Why is the Chronic Lymphocytic Leukemia (CLL) Comprehensive Diagnostic Panel Test Taken?

The Chronic Lymphocytic Leukemia (CLL) Comprehensive Diagnostic Panel test is taken to diagnose and monitor Chronic Lymphocytic Leukemia, a type of cancer that affects the blood and bone marrow. This test helps in determining the presence of abnormal lymphocytes in the blood, which are characteristic of CLL.

The test may include various components such as:

  • Complete blood count (CBC) to check the number of blood cells
  • Peripheral blood smear to examine the appearance of blood cells under a microscope
  • Flow cytometry to analyze the presence of specific markers on the surface of blood cells
  • Cytogenetic analysis to identify any genetic abnormalities
  • Molecular testing to detect specific gene mutations

By analyzing these components, healthcare providers can determine the stage of CLL, monitor disease progression, and guide treatment decisions. Regular monitoring of CLL through this comprehensive diagnostic panel is crucial for managing the disease effectively and improving outcomes for patients.

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