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Parameters

Reports Within:

Parameter Include:

Requisites
Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days the report can be obtained for the test Neuronal (Paraneoplastic) Antibody Panel (12 Parameters) is 7 days.

What are the prerequisites for the test Neuronal (Paraneoplastic) Antibody Panel (12 Parameters)

  • Specimen: Serum
  • Volume: 2 mL
  • Minimum Volume: 0.5 mL
  • Collection Container: Red top tube or gel-barrier tube
  • Storage Instructions: Maintain specimen at room temperature
  • Stability: Stable at room temperature for 5 days
  • Rejection Criteria: Grossly hemolyzed specimens
  • Transport Temperature: Room temperature
  • Methodology: Enzyme-Linked Immunosorbent Assay (ELISA)
  • Turnaround Time: 7 days
  • Reference Range: Negative
  • Clinical Significance: Detects antibodies associated with paraneoplastic neurological syndromes

What are the measure values for the test Neuronal (Paraneoplastic) Antibody Panel (12 Parameters)

Antibody Reference Range
Anti-Hu 0-1.0 Units
Anti-Ri 0-1.0 Units
Anti-Yo 0-1.0 Units
Anti-Tr 0-1.0 Units
Anti-CV2/CRMP5 0-1.0 Units
Amphiphysin (IgG) 0-1.0 Units
Anti-Ma2/Ta 0-1.0 Units
PCA-1 (Anti-Tr/DNER) 0-1.0 Units
ANNA-3 (Anti-Tr/DNER) 0-1.0 Units
PCA-2 (Anti-Yo) 0-1.0 Units
PCA-Tr (Anti-Tr) 0-1.0 Units
AGNA-1 (Anti-Hu) 0-1.0 Units

What does this test Neuronal (Paraneoplastic) Antibody Panel (12 Parameters) identify?

Neuronal (Paraneoplastic) Antibody Panel (12 Parameters)

The Neuronal (Paraneoplastic) Antibody Panel is a test that identifies antibodies that are associated with neurological paraneoplastic syndromes. These syndromes are a group of rare disorders that are triggered by an abnormal immune response to cancer in the body. The antibodies in this panel are directed against antigens that are expressed by both the tumor cells and the nervous system.

The panel includes 12 parameters that test for specific antibodies, including anti-Hu, anti-Yo, anti-Ri, anti-Ma2, anti-CV2, anti-Amphiphysin, anti-Tr (DNER), anti-SOX1, anti-GAD65, anti-VGKC complex, anti-NMDA receptor, and anti-AMPAR. These antibodies are associated with a variety of paraneoplastic syndromes, such as limbic encephalitis, cerebellar degeneration, opsoclonus-myoclonus syndrome, and stiff-person syndrome.

By identifying these antibodies, healthcare providers can diagnose paraneoplastic syndromes early and implement appropriate treatment strategies to manage the neurological symptoms and underlying cancer.

Why is this test Neuronal (Paraneoplastic) Antibody Panel (12 Parameters) taken?

  1. Neuronal (Paraneoplastic) Antibody Panel (12 Parameters) test is taken to help diagnose autoimmune disorders affecting the nervous system.
  2. It is used to detect antibodies that target proteins found in the brain and nerves.
  3. These antibodies are often associated with paraneoplastic syndromes, which are neurological disorders triggered by an underlying cancer.
  4. The test can help identify specific antibodies that may be causing neurologic symptoms in a patient.
  5. Results from this test can aid in determining the appropriate treatment and management plan for patients with autoimmune neurological conditions.

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