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Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days the report can be obtained for the ALK Resistance Mutations Test By NGS is typically 7-10 business days from receipt of the sample at the laboratory.

What are the prerequisites for the test ALK Resistance Mutations Test By NGS

  • Patient must have a confirmed diagnosis of non-small cell lung cancer (NSCLC)
  • Patient must have a positive ALK gene rearrangement status
  • Patient must have progressed on ALK inhibitor therapy
  • Specimen type required: Formalin-fixed, paraffin-embedded (FFPE) tumor tissue

What are the measure values for the test ALK Resistance Mutations Test By NGS

  • Test Name: ALK Resistance Mutations Test By NGS
  • Measure Values:
    • Gene Alterations Detected: ALK resistance mutations
    • Methodology: Next-Generation Sequencing (NGS)
    • Turnaround Time: 7-10 days
    • Specimen Type: Formalin-fixed paraffin-embedded tissue
    • Specimen Requirements: 10 unstained slides or 1 FFPE block
    • Reference Range: Negative for ALK resistance mutations
    • Clinical Significance: Detection of ALK resistance mutations can help guide treatment decisions for patients with ALK-positive cancers who have developed resistance to targeted therapies

What does this test ALK Resistance Mutations Test By NGS identify?

  • Identifies mutations in the ALK gene that may confer resistance to ALK inhibitors
  • Helps in determining the most effective treatment for patients with ALK-positive cancers
  • Provides information on potential resistance mechanisms that may develop during targeted therapy
  • Guides clinicians in making informed decisions regarding treatment options and personalized medicine strategies

Why is this test ALK Resistance Mutations Test By NGS taken?

Reasons for taking the ALK Resistance Mutations Test By NGS:

  • Personalized Treatment: The test helps in identifying specific mutations in the ALK gene that are associated with resistance to ALK inhibitor therapy. This information can guide healthcare providers in selecting the most effective treatment for the patient.
  • Monitoring Disease Progression: By detecting ALK resistance mutations early on, the test can help in monitoring disease progression and determining the need for changes in treatment plans.
  • Predicting Response to Therapy: Knowing the presence of ALK resistance mutations can provide insights into how well a patient may respond to ALK inhibitor therapy, allowing for more informed decision-making in terms of treatment options.
  • Clinical Management: The test results can aid in clinical management by providing valuable information on the genetic profile of the tumor, which can help in assessing the overall prognosis and designing a personalized treatment strategy.
  • Research Purposes: The test can also be used for research purposes to further understand the mechanisms of resistance to ALK inhibitors and develop new therapeutic approaches.

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