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Parameters

Reports Within:

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Requisites
Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum number of days the report can be obtained for the Microsatellite Instability (MSI) Test By PCR is 10 days.

What are the prerequisites for the test Microsatellite Instability (MSI) Test By PCR

  • Patient sample: Tumor tissue from the patient
  • PCR machine
  • Primers for the target microsatellite loci
  • DNA extraction kit
  • PCR reagents (buffer, dNTPs, Taq polymerase)
  • Gel electrophoresis equipment
  • PCR analysis software

What are the measure values for the test Microsatellite Instability (MSI) Test By PCR

  • MSI-High: MSI-High indicates that there are alterations in the microsatellite regions of the DNA, which may be indicative of Lynch syndrome or sporadic colorectal cancer. This result is typically classified as MSI-High when ≥30% of the markers tested show instability.
  • MSI-Low: MSI-Low indicates a lower level of microsatellite instability, which may be seen in some sporadic colorectal cancers. This result is typically classified as MSI-Low when <30% of the markers tested show instability.
  • MSS: MSS (Microsatellite Stable) indicates that there is no microsatellite instability detected in the markers tested. This result is typically classified as MSS when none of the markers show instability.

What does this test Microsatellite Instability (MSI) Test By PCR identify?

  • Microsatellite Instability (MSI) Test By PCR identifies abnormalities in the number of repeats in microsatellite sequences in DNA.
  • Microsatellites are short repeated sequences of DNA that are prone to replication errors.
  • MSI can be a sign of defects in DNA mismatch repair mechanisms, which can lead to the development of certain types of cancer.
  • The PCR technique is used to amplify specific microsatellite regions in the DNA sample, allowing for the detection of any instability in these regions.
  • The MSI test can be used to screen for Lynch syndrome, a hereditary condition that predisposes individuals to certain types of cancer.

Why is this test Microsatellite Instability (MSI) Test By PCR taken?

Microsatellite Instability (MSI) Test By PCR is taken to identify any abnormalities in the DNA that can indicate a predisposition to certain types of cancer, such as colorectal cancer. The test looks for changes in the length of microsatellites, which are short repeated sequences of DNA that are prone to errors during cell division. MSI can be caused by defects in DNA repair mechanisms and is commonly found in individuals with Lynch syndrome, a genetic condition that increases the risk of developing certain types of cancer.

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