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Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The report for the HLA DRB1, DQB1 & DPB1 (Class II) Typing Test can be obtained within a maximum of 10 business days from the date of sample collection.

What are the prerequisites for the test HLA DRB1, DQB1 & DPB1 (Class II) Typing Test

  • Sample Type: Whole blood in EDTA
  • Sample Volume: 3-5 mL
  • Minimum Volume: 1 mL
  • Storage and Transport: Ambient
  • Specimen Stability: ≥ 7 days at ambient temperature
  • Rejection Criteria: Clotted, hemolyzed, or severely lipemic samples

What are the measure values for the test HLA DRB1, DQB1 & DPB1 (Class II) Typing Test

  • HLA DRB1: The measure values for this test include a combination of letters and numbers that represent the specific alleles present in an individual's HLA DRB1 gene. For example, a result may be DRB1*04:01/DRB1*15:01, indicating the presence of the DRB1*04:01 and DRB1*15:01 alleles.
  • HLA DQB1: Similar to HLA DRB1, the measure values for HLA DQB1 include specific allele combinations such as DQB1*03:01/DQB1*06:02, indicating the presence of the DQB1*03:01 and DQB1*06:02 alleles.
  • HLA DPB1: The measure values for this test also involve allele combinations specific to the HLA DPB1 gene. An example result may be DPB1*02:01/DPB1*04:01, indicating the presence of the DPB1*02:01 and DPB1*04:01 alleles.

What does this test HLA DRB1, DQB1 & DPB1 (Class II) Typing Test identify?

This test, HLA DRB1, DQB1 & DPB1 (Class II) Typing Test, identifies specific human leukocyte antigen (HLA) genes within the Class II region. The HLA genes encode proteins that are important for the regulation of the immune system and play a critical role in immune response and self-recognition.

By typing these HLA genes, healthcare providers can assess an individual's genetic predisposition to certain autoimmune diseases, infectious diseases, and other conditions. This information can be used to guide treatment decisions, predict disease susceptibility, and improve transplantation outcomes.

Why is this test HLA DRB1, DQB1 & DPB1 (Class II) Typing Test taken?

HLA DRB1, DQB1 & DPB1 (Class II) Typing Test is taken to determine the specific human leukocyte antigen (HLA) alleles present in an individual. The HLA system plays a crucial role in the immune response by helping the body recognize foreign substances, such as bacteria and viruses, and mount an immune response against them.

By analyzing the HLA DRB1, DQB1, and DPB1 genes, healthcare providers can assess an individual's risk of developing certain autoimmune diseases, such as type 1 diabetes, rheumatoid arthritis, and celiac disease. Additionally, HLA typing is important for organ and tissue transplantation, as matching the donor and recipient HLA alleles can reduce the risk of rejection.

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