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Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

Maximum days to obtain the report for the test EML4 ALK Translocation Test By FISH: 10-14 days

What are the prerequisites for the test EML4 ALK Translocation Test By FISH

  • Specimen Type: Formalin-fixed, paraffin-embedded tissue block or slides
  • Specimen Size: Minimum of one 4-micron thick section
  • Specimen Handling: Tissue must be fixed in 10% neutral buffered formalin for at least 6-72 hours and stored at room temperature
  • Turnaround Time: 3-5 days
  • Test Method: Fluorescence in situ hybridization (FISH)
  • Test Limitations: Results may be affected by the quality of the specimen or technical factors

What are the measure values for the test EML4 ALK Translocation Test By FISH

  • Positive: Presence of EML4-ALK translocation
  • Negative: Absence of EML4-ALK translocation
  • Indeterminate: Inconclusive result, further testing may be required

What does this test EML4 ALK Translocation Test By FISH identify?

The EML4 ALK Translocation Test By FISH is a diagnostic test used to identify the presence of a fusion gene involving the EML4 (echinoderm microtubule-associated protein-like 4) and ALK (anaplastic lymphoma kinase) genes in cancer cells.

This test is commonly used in the diagnosis and management of non-small cell lung cancer (NSCLC). The EML4-ALK fusion gene is found in a subset of NSCLC patients and is associated with a specific response to targeted therapy with ALK inhibitors.

By identifying the EML4-ALK fusion gene, this test helps oncologists determine the most appropriate treatment options for NSCLC patients, such as ALK inhibitor therapy. It also provides valuable prognostic information and can help guide personalized treatment decisions.

Why is this test EML4 ALK Translocation Test By FISH taken?

The EML4 ALK Translocation Test By FISH is taken to detect the presence of a fusion gene involving the EML4 and ALK genes. This fusion gene is found in a subset of non-small cell lung cancers and is associated with increased response to specific targeted therapies, such as ALK inhibitors.

By identifying the EML4 ALK translocation, healthcare providers can determine the most appropriate treatment options for patients with non-small cell lung cancer, leading to better outcomes and potentially improved quality of life.

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