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Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

Maximum Days to Obtain Report for JAK2 V617 Reflex Panel:

  • Standard Turnaround Time: 7 days
  • Rush Service (additional fee): 3 days
  • Expedited Service (additional fee): 1 day

What are the prerequisites for the test JAK2 V617 Reflex Panel

  • Complete blood count (CBC)
  • Peripheral blood smear review
  • Physical examination
  • Patient history

What are the measure values for the test JAK2 V617 Reflex Panel

  • JAK2 V617F Mutation Analysis: Detected or Not Detected
  • JAK2 Exon 12 Mutation Analysis: Detected or Not Detected

What does this test JAK2 V617 Reflex Panel identify?

  • JAK2 V617F mutation: This test identifies a specific mutation in the JAK2 gene, known as the V617F mutation. This mutation is commonly found in patients with myeloproliferative neoplasms (MPNs) such as polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Detection of this mutation can help in the diagnosis and monitoring of these conditions.
  • Reflex Testing: The reflex panel may include additional tests such as JAK2 exon 12 mutation analysis or other molecular tests to further characterize the specific MPN subtype in patients with suspected MPNs.

Why is this test JAK2 V617 Reflex Panel taken?

  1. JAK2 V617F mutation is a genetic change that is associated with some blood disorders, including myeloproliferative neoplasms such as polycythemia vera, essential thrombocythemia, and primary myelofibrosis.
  2. This test is typically ordered when a person shows symptoms suggestive of a myeloproliferative neoplasm, such as abnormal blood cell counts, enlarged spleen, or unexplained blood clots.
  3. The JAK2 V617F mutation test helps in diagnosing and monitoring these blood disorders, as well as determining the likelihood of disease progression and response to treatment.
  4. If the initial JAK2 V617F mutation test is positive, a reflex panel may be ordered to further characterize the mutation and assess additional genetic changes that may be present.
  5. Overall, the JAK2 V617F reflex panel aids in the accurate diagnosis and management of myeloproliferative neoplasms, guiding healthcare providers in developing appropriate treatment plans for affected individuals.

Popular FAQs on Test

The JAK2 V617F Reflex Panel test is a diagnostic test used to detect mutations in the JAK2 gene, specifically the V617F mutation. This mutation is commonly found in patients with myeloproliferative neoplasms, such as polycythemia vera, essential thrombocythemia, and primary myelofibrosis.
The JAK2 V617F Reflex Panel test is performed to help diagnose myeloproliferative neoplasms. It is often ordered when a healthcare provider suspects that a patient may have one of these conditions based on their symptoms and other laboratory tests.
The JAK2 V617F Reflex Panel test is typically performed on a blood sample. The sample is analyzed in a laboratory using molecular testing techniques to detect the presence of the JAK2 V617F mutation.
The results of the JAK2 V617F Reflex Panel test can be positive, indicating the presence of the JAK2 V617F mutation, or negative, indicating the absence of the mutation. A positive result may suggest a diagnosis of a myeloproliferative neoplasm, while a negative result does not rule out the possibility of the condition.
The JAK2 V617F Reflex Panel test is highly accurate in detecting the JAK2 V617F mutation. However, it is important to note that a negative result does not completely rule out the possibility of a myeloproliferative neoplasm, as other mutations or factors may be involved.

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