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Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days the report can be obtained for the Fanconi Anemia (FA) Stress Cytogenetics Test is typically around 14-21 days. However, this timeline can vary depending on the specific laboratory or testing facility performing the analysis.

What are the prerequisites for the test Fanconi Anemia (FA) Stress Cytogenetics Test

  • Patients must have a suspected or confirmed diagnosis of Fanconi Anemia (FA)
  • Patients must have a blood sample collected for cytogenetic testing
  • Patients must have received genetic counseling and have a thorough understanding of the test and its implications
  • Patients must not have any contraindications for blood sample collection
  • Patients must be willing to undergo testing and follow-up care as recommended by their healthcare provider

What are the measure values for the test Fanconi Anemia (FA) Stress Cytogenetics Test

  • Chromosomal breakage: Increased chromosomal breakage observed in FA patients compared to normal individuals
  • Radiomimetic agents: Increased sensitivity to radiomimetic agents such as diepoxybutane (DEB) or mitomycin C (MMC)
  • Cell culture: Cells from FA patients typically show hypersensitivity to DNA crosslinking agents in cell culture
  • Chromosome analysis: Presence of radial figures, breaks, rearrangements, and other chromosomal abnormalities in FA patients

What does this test Fanconi Anemia (FA) Stress Cytogenetics Test identify?

The Fanconi Anemia (FA) Stress Cytogenetics Test is a diagnostic test that identifies chromosomal abnormalities associated with Fanconi Anemia, a rare genetic disorder characterized by bone marrow failure, physical abnormalities, and an increased risk of cancer. This test specifically looks for chromosomal breakage and rearrangements in response to DNA damaging agents, such as diepoxybutane (DEB) or mitomycin C (MMC), which are characteristic of FA.

Why is this test Fanconi Anemia (FA) Stress Cytogenetics Test taken?

The Fanconi Anemia (FA) Stress Cytogenetics Test is taken to diagnose Fanconi Anemia, a rare genetic disorder that affects the bone marrow and leads to decreased production of all types of blood cells. This test is specifically used to assess the ability of a patient's cells to repair DNA damage, which is a key characteristic of Fanconi Anemia.

The test involves exposing the patient's cells to a chemical that induces DNA damage, and then examining the cells under a microscope to see if they are able to repair the damage. Patients with Fanconi Anemia typically have cells that are unable to repair DNA damage properly, which can be seen in the results of the test.

In addition to diagnosing Fanconi Anemia, this test can also be used to assess the risk of developing cancer in patients with the disorder, as well as to guide treatment decisions. Overall, the FA Stress Cytogenetics Test plays a crucial role in the diagnosis and management of Fanconi Anemia.

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