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Requisites
Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days the report can be obtained for the test PML Ra Ra t(15:17), Quantitative Test is 7 days.

What are the prerequisites for the test PML Ra Ra t(15:17), Quantitative Test

  • Basic knowledge of mathematics
  • Understanding of algebraic expressions
  • Familiarity with mathematical operations (addition, subtraction, multiplication, division)
  • Ability to interpret graphs and charts
  • Problem-solving skills
  • Knowledge of percentages, ratios, fractions, and decimals
  • Ability to work with geometric shapes and measurements

What are the measure values for the test PML Ra Ra t(15:17), Quantitative Test

  • Positive: Greater than or equal to 0.1 PML/Ra ratio
  • Negative: Less than 0.1 PML/Ra ratio

What does this test PML Ra Ra t(15:17), Quantitative Test identify?

  1. This test identifies the presence of the PML-RARα fusion gene, which is characteristic of acute promyelocytic leukemia (APL).
  2. The t(15:17) translocation results in the fusion of the promyelocytic leukemia (PML) gene on chromosome 15 with the retinoic acid receptor alpha (RARα) gene on chromosome 17.
  3. Quantitative testing measures the amount of PML-RARα fusion gene present in the sample, which can help in monitoring the disease progression and response to treatment.
  4. Identification of the PML-RARα fusion gene is crucial for the diagnosis and management of APL, as it is a specific molecular marker for this subtype of leukemia.

Why is this test PML Ra Ra t(15:17), Quantitative Test taken?

Reason for Taking the PML Ra Ra t(15:17), Quantitative Test

The PML Ra Ra t(15:17), Quantitative Test is taken to detect and monitor the presence of a specific genetic abnormality known as t(15:17) in patients with acute promyelocytic leukemia (APL). This translocation involves the fusion of the PML gene on chromosome 15 and the RARα gene on chromosome 17, resulting in the formation of a fusion gene that plays a key role in the development of APL.

By performing this test, healthcare providers can accurately diagnose APL, assess the risk of relapse, and monitor the response to treatment. The quantitative aspect of the test helps in determining the level of the fusion gene in the patient's cells, which can provide valuable information about the disease burden and treatment efficacy.

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