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Requisites
Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days the report can be obtained for the test IGH/CCND1 t(11;14) (q13;q32) Test By FISH is typically 7-10 business days.

What are the prerequisites for the test IGH/CCND1 t(11;14) (q13;q32) Test By FISH

  • Specimen Type: Fixed Tissue
  • Specimen Size: Minimum of 5 mm in diameter
  • Specimen Fixative: Formalin
  • Specimen Storage: Room temperature
  • Specimen Stability: Stable at room temperature for at least 1 year
  • Rejection Criteria: Inadequate specimen size, improper fixative

What are the measure values for the test IGH/CCND1 t(11;14) (q13;q32) Test By FISH

  • Positive: Presence of IGH/CCND1 fusion signal in at least 15% of analyzed cells
  • Negative: Absence of IGH/CCND1 fusion signal in analyzed cells
  • Indeterminate: Inconclusive result due to insufficient or poor quality cells

What does this test IGH/CCND1 t(11;14) (q13;q32) Test By FISH identify?

This test identifies the translocation between the IGH gene on chromosome 14 and the CCND1 gene on chromosome 11. This translocation is associated with various types of lymphoma, such as mantle cell lymphoma. The t(11;14) (q13;q32) translocation results in the overexpression of the CCND1 gene, leading to uncontrolled cell proliferation and tumorigenesis.

Why is this test IGH/CCND1 t(11;14) (q13;q32) Test By FISH taken?

The IGH/CCND1 t(11;14) (q13;q32) test by FISH is taken to detect a specific translocation between the IGH gene on chromosome 14 and the CCND1 gene on chromosome 11. This translocation is commonly found in patients with mantle cell lymphoma, a type of non-Hodgkin lymphoma.

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