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Parameters

Reports Within:

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Requisites
Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days the report can be obtained for the test Leukocyte Adhesion Deficiency (LAD) Test is 7 days.

What are the prerequisites for the test Leukocyte Adhesion Deficiency (LAD) Test

  • Complete blood count (CBC)
  • White blood cell differential count
  • Flow cytometry to measure expression of adhesion molecules on leukocytes
  • Genetic testing to confirm mutations in the ITGB2 gene

What are the measure values for the test Leukocyte Adhesion Deficiency (LAD) Test

  • Leukocyte Adhesion Deficiency (LAD) Test
    • Neutrophil count: 1,500-8,000 cells/mcL
    • CD18 expression on neutrophils: Normal >1500 mfi

What does this test Leukocyte Adhesion Deficiency (LAD) Test identify?

The Leukocyte Adhesion Deficiency (LAD) Test identifies a rare genetic disorder that affects the immune system. This disorder causes white blood cells to be unable to properly stick to blood vessel walls and migrate to sites of infection or inflammation. As a result, individuals with LAD have a weakened immune response and are more susceptible to recurrent infections.

Why is this test Leukocyte Adhesion Deficiency (LAD) Test taken?

Leukocyte Adhesion Deficiency (LAD) Test is taken to diagnose a rare genetic disorder that affects the immune system. Individuals with LAD have a deficiency in certain proteins that are responsible for allowing white blood cells to stick to the walls of blood vessels and move towards sites of infection or inflammation. This results in impaired immune response and recurrent bacterial infections.

The test is typically recommended for individuals who have recurrent or severe bacterial infections, delayed wound healing, and other symptoms suggestive of LAD. It helps in confirming the diagnosis and guiding appropriate treatment strategies.

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