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Reports Within

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Reports Within:

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Requisites
Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days for obtaining the report for the IGH/MAF t(14;16) Test By FISH is typically 7-10 business days. However, this timeframe may vary depending on the specific laboratory or healthcare provider conducting the test.

What are the prerequisites for the test IGH/MAF t(14;16) Test By FISH

  • Specimen Type: Bone Marrow
  • Container/Tube: Green-top (sodium heparin)
  • Specimen Volume: 2-3 mL
  • Collection Instructions: Invert several times to mix blood. Forward unprocessed whole blood promptly at ambient temperature. Do not freeze whole blood. Transport 1 mL bone marrow in a green-top (sodium heparin) tube.
  • Stability: Ambient: 72 hours; Refrigerated: 7 days

What are the measure values for the test IGH/MAF t(14;16) Test By FISH

  • Positive: Presence of IGH/MAF fusion signal in ≥20% of interphase nuclei
  • Negative: Absence of IGH/MAF fusion signal or presence in <20% of interphase nuclei

What does this test IGH/MAF t(14;16) Test By FISH identify?

IGH/MAF t(14;16) Test By FISH

The IGH/MAF t(14;16) test by FISH is a diagnostic test that identifies a specific chromosomal translocation between the immunoglobulin heavy chain (IGH) gene on chromosome 14 and the MAF gene on chromosome 16. This translocation is associated with certain types of cancer, particularly multiple myeloma.

Fluorescence in situ hybridization (FISH) is a molecular technique used to detect specific DNA sequences in cells. In this test, fluorescent probes are used to bind to the IGH and MAF genes, allowing for visualization of the translocation.

Identifying the IGH/MAF t(14;16) translocation can help healthcare providers make a more accurate diagnosis and determine the most appropriate treatment plan for patients with multiple myeloma or other related cancers.

Why is this test IGH/MAF t(14;16) Test By FISH taken?

IGH/MAF t(14;16) Test By FISH

The IGH/MAF t(14;16) Test By FISH is taken to detect a specific translocation between chromosomes 14 and 16 in the DNA. This translocation is commonly associated with certain types of cancer, particularly multiple myeloma.

By identifying the presence of the t(14;16) translocation using Fluorescence In Situ Hybridization (FISH) technique, doctors can diagnose and monitor the progression of multiple myeloma and determine the appropriate treatment plan for the patient.

Popular FAQs on Test

The IGH/MAF t(14;16) Test By FISH is a laboratory test used to detect a specific genetic abnormality involving the translocation of chromosomes 14 and 16 in cells. This abnormality is associated with certain types of cancer, including multiple myeloma.
The IGH/MAF t(14;16) Test By FISH is performed to help diagnose and monitor certain types of cancer, particularly multiple myeloma. It can also be used to determine the prognosis and guide treatment decisions for patients with this genetic abnormality.
The IGH/MAF t(14;16) Test By FISH is performed on a sample of cells, typically obtained from a bone marrow biopsy or blood sample. The cells are analyzed using a technique called fluorescence in situ hybridization (FISH) to detect the translocation of chromosomes 14 and 16.
The IGH/MAF t(14;16) Test By FISH is not typically painful for the patient. The sample collection may involve some discomfort, such as a needle stick for a bone marrow biopsy, but the actual FISH testing is done in the laboratory and does not cause any pain.
The IGH/MAF t(14;16) Test By FISH is a relatively safe and low-risk procedure. The main risks are related to the sample collection process, such as bleeding or infection at the biopsy site. However, these risks are rare and are typically minor.

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