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Requisites
Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days the report can be obtained for the IGH/FGFR3 t(4;14) Test By FISH is typically 7-10 business days.

What are the prerequisites for the test IGH/FGFR3 t(4;14) Test By FISH

  • Specimen Type: Bone marrow aspirate or peripheral blood
  • Specimen Volume: 2-5 mL bone marrow or 3-5 mL peripheral blood
  • Specimen Container: Lavender top (EDTA) tube for bone marrow or yellow top (ACD) tube for peripheral blood
  • Collection: Collect specimen aseptically and mix well
  • Transport: Send specimen to the laboratory at room temperature
  • Turnaround Time: 3-5 days

What are the measure values for the test IGH/FGFR3 t(4;14) Test By FISH

  • Positive: Fusion signals (IGH/FGFR3) observed in more than 20% of analyzed cells
  • Negative: Fusion signals (IGH/FGFR3) observed in 20% or less of analyzed cells

What does this test IGH/FGFR3 t(4;14) Test By FISH identify?

The IGH/FGFR3 t(4;14) Test By FISH is a genetic test that identifies a specific translocation between chromosomes 4 and 14. This test uses fluorescence in situ hybridization (FISH) to detect rearrangements involving the immunoglobulin heavy chain (IGH) gene on chromosome 14 and the fibroblast growth factor receptor 3 (FGFR3) gene on chromosome 4.

Identifying this translocation can be important in the diagnosis and management of certain types of cancer, particularly multiple myeloma. The presence of the IGH/FGFR3 t(4;14) translocation can impact treatment decisions and prognosis for individuals with this genetic abnormality.

Why is this test IGH/FGFR3 t(4;14) Test By FISH taken?

IGH/FGFR3 t(4;14) Test By FISH

The IGH/FGFR3 t(4;14) Test By FISH is performed to detect a specific chromosomal abnormality in certain types of cancer, such as multiple myeloma. This test uses Fluorescence In Situ Hybridization (FISH) technology to identify the translocation of genetic material between the IGH gene on chromosome 14 and the FGFR3 gene on chromosome 4.

This translocation can have diagnostic and prognostic implications for patients with multiple myeloma, as it is associated with a more aggressive form of the disease. Identifying this chromosomal abnormality can help oncologists tailor treatment plans and predict patient outcomes more accurately.

Overall, the IGH/FGFR3 t(4;14) Test By FISH plays a crucial role in the diagnosis and management of certain cancers, providing valuable information that can guide personalized treatment decisions.

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