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Reports Within

Parameters

Reports Within:

Parameter Include:

Requisites
Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days for obtaining the report for the test E2A (TCF3) Breakapart Test By FISH is typically 5-7 business days.

What are the prerequisites for the test E2A (TCF3) Breakapart Test By FISH

  • Patient sample: The test requires a fresh or formalin-fixed, paraffin-embedded tissue sample to be collected from the patient.
  • Proper specimen handling: The specimen must be handled carefully to prevent any degradation of the DNA.
  • Qualified laboratory: The test should be performed in a qualified laboratory by trained technicians.
  • Reagents and probes: The laboratory should have the necessary reagents and probes specific for the E2A (TCF3) gene breakapart test.
  • Equipment: The laboratory should have the appropriate equipment for performing the fluorescence in situ hybridization (FISH) technique.

What are the measure values for the test E2A (TCF3) Breakapart Test By FISH

  • Positive Result: Rearrangement of the E2A (TCF3) gene detected
  • Negative Result: No rearrangement of the E2A (TCF3) gene detected
  • Indeterminate Result: Inconclusive result, further testing may be required

What does this test E2A (TCF3) Breakapart Test By FISH identify?

  • Test Name: E2A (TCF3) Breakapart Test By FISH
  • Identifies: This test uses Fluorescence In Situ Hybridization (FISH) technique to identify rearrangements involving the E2A (TCF3) gene. The breakapart probe used in this test specifically targets the E2A gene and can detect translocations, inversions, and other structural abnormalities affecting this gene.
  • Significance: The E2A gene encodes a transcription factor that plays a critical role in the regulation of gene expression and cell differentiation. Rearrangements involving the E2A gene have been implicated in various hematologic malignancies, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). Identification of E2A gene rearrangements can help in the diagnosis, prognosis, and treatment planning for patients with these types of cancers.

Why is this test E2A (TCF3) Breakapart Test By FISH taken?

  • Reason for Test: The E2A (TCF3) Breakapart Test by FISH is taken to detect rearrangements involving the TCF3 gene, which is important for normal cell growth and development. Rearrangements in this gene can be associated with certain types of leukemia, lymphoma, and other cancers.
  • Method of Test: Fluorescence in situ hybridization (FISH) is used to identify and visualize specific DNA sequences within chromosomes. In the case of the E2A (TCF3) Breakapart Test, probes are used to detect breaks or rearrangements in the TCF3 gene.
  • Interpretation of Results: A positive result for a break or rearrangement in the TCF3 gene may indicate a potential genetic abnormality that could be contributing to the development or progression of cancer. Further testing and evaluation by a healthcare provider may be necessary to determine the appropriate course of treatment.

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