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Number of red blood cells in the blood

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Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days for obtaining a report for the AML/ETO t(8;21) Test By FISH is 7 days.

What are the prerequisites for the test AML/ETO t(8;21) Test By FISH

  • Specimen: Bone marrow aspirate or peripheral blood
  • Requisition form: Properly filled out with patient information
  • Consent form: Signed by the patient or legal guardian
  • Test request: Ordered by a licensed healthcare provider
  • Proper sample collection: Collected by a trained phlebotomist or healthcare provider
  • Transportation: Sample should be transported to the lab in a timely manner
  • Storage: Sample should be stored according to lab guidelines

What are the measure values for the test AML/ETO t(8;21) Test By FISH

  • Positive: Presence of AML/ETO fusion gene
  • Negative: Absence of AML/ETO fusion gene
  • Indeterminate: Inconclusive result, further testing may be needed

What does this test AML/ETO t(8;21) Test By FISH identify?

This test identifies the presence of the AML/ETO t(8;21) translocation in individuals with acute myeloid leukemia (AML). This translocation involves a fusion of the AML1 gene on chromosome 21 with the ETO gene on chromosome 8, resulting in a chimeric gene known as AML1-ETO. This genetic abnormality is associated with a specific subtype of AML and can help guide treatment decisions and predict prognosis for patients.

Why is this test AML/ETO t(8;21) Test By FISH taken?

AML/ETO t(8;21) Test By FISH

Why is this test taken?

The AML/ETO t(8;21) test by FISH is taken to detect the presence of a specific chromosomal abnormality in a person's bone marrow cells. This abnormality, known as the t(8;21) translocation, is commonly found in patients with acute myeloid leukemia (AML).

By identifying this translocation, healthcare providers can make a more accurate diagnosis of AML and determine the appropriate treatment plan for the patient. This test is particularly useful in distinguishing AML with t(8;21) from other types of leukemia that may have similar symptoms but require different treatment approaches.

Overall, the AML/ETO t(8;21) test by FISH plays a crucial role in the diagnosis and management of AML, helping healthcare providers tailor treatment strategies to individual patients based on their specific genetic abnormalities.

Popular FAQs on Test

The AML/ETO t(8;21) Test By FISH is a laboratory test that uses fluorescence in situ hybridization (FISH) to detect a specific genetic abnormality known as the t(8;21) translocation. This translocation is commonly found in patients with acute myeloid leukemia (AML) and is associated with a more favorable prognosis.
During the test, a sample of the patient's bone marrow or blood cells is collected and treated with special fluorescent probes that specifically bind to the AML/ETO fusion gene created by the t(8;21) translocation. The cells are then examined under a fluorescence microscope to see if the fusion gene is present.
A positive result on the test indicates that the AML/ETO fusion gene created by the t(8;21) translocation is present in the patient's cells. This genetic abnormality is commonly associated with a specific subtype of AML known as AML with t(8;21), which has a more favorable prognosis compared to other subtypes of AML.
A negative result on the test indicates that the AML/ETO fusion gene is not present in the patient's cells. This may suggest that the patient's AML is not associated with the t(8;21) translocation and may have a different genetic profile and prognosis.
The AML/ETO t(8;21) Test By FISH is not a definitive diagnostic test for AML on its own. It is typically used in conjunction with other laboratory tests, such as cytogenetic analysis and molecular testing, to help confirm a diagnosis of AML and provide additional prognostic information.

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