Your Cart Item
Reports Within

Parameters

Reports Within:

Parameter Include:

Requisites
Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

60
Mins

Homes

1M
Happy

Customers

4.9
Google

Rating

Certified

Labs

What is the maximum days the report can be obtained for the test

The maximum days the report can be obtained for the test RUNX-RUNX1 t(8;21) (q22;q22) Test By FISH is 7-10 days.

What are the prerequisites for the test RUNX-RUNX1 t(8;21) (q22;q22) Test By FISH

  • Peripheral blood or bone marrow sample
  • Specimen must be collected in a sodium heparin tube
  • Specimen must be received within 24 hours of collection
  • Patient information including name, date of birth, and medical record number
  • Requisition form with test request

What are the measure values for the test RUNX-RUNX1 t(8;21) (q22;q22) Test By FISH

  • Test: RUNX-RUNX1 t(8;21) (q22;q22) Test By FISH
  • Measure Values:
    • Positive: Presence of t(8;21) translocation in RUNX-RUNX1 gene fusion
    • Negative: Absence of t(8;21) translocation in RUNX-RUNX1 gene fusion

What does this test RUNX-RUNX1 t(8;21) (q22;q22) Test By FISH identify?

Test: RUNX-RUNX1 t(8;21) (q22;q22) Test By FISH

This test is used to identify a specific chromosomal translocation, t(8;21)(q22;q22), involving the genes RUNX1 and RUNX1T1. This translocation is associated with a subtype of acute myeloid leukemia (AML) known as AML with t(8;21)(q22;q22).

Fluorescence in situ hybridization (FISH) is a molecular cytogenetic technique that uses fluorescent probes to detect specific DNA sequences on chromosomes. In the case of the RUNX-RUNX1 t(8;21) test, FISH is used to identify the translocation between chromosomes 8 and 21.

By analyzing the presence of the RUNX1-RUNX1T1 fusion gene, this test can confirm the diagnosis of AML with t(8;21)(q22;q22) and help guide treatment decisions for patients with this specific genetic abnormality.

Why is this test RUNX-RUNX1 t(8;21) (q22;q22) Test By FISH taken?

The test for RUNX-RUNX1 t(8;21) (q22;q22) by FISH is taken to detect the presence of a specific chromosomal translocation between chromosomes 8 and 21. This translocation results in a fusion gene between the RUNX1 gene on chromosome 21 and the RUNX1T1 gene on chromosome 8.

This test is important in the diagnosis and prognosis of certain types of leukemia, specifically acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). The presence of the t(8;21) translocation is associated with a more favorable prognosis in AML patients, while it may indicate a poorer prognosis in ALL patients.

By using fluorescence in situ hybridization (FISH) technology, this test can accurately identify the translocation at the molecular level, providing valuable information for treatment planning and monitoring of the disease.

No FAQs available.

Customer Google Rating