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Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days the report can be obtained for the test PDGFR Alpha (4q12) Gene Rearrangement Test By FISH is typically within 7-10 business days from the time the sample is received in the laboratory.

What are the prerequisites for the test PDGFR Alpha (4q12) Gene Rearrangement Test By FISH

  • Specimen Type: Formalin-fixed, paraffin-embedded (FFPE) tissue block
  • Specimen Size: Minimum of 5 unstained slides with at least 10% tumor cells
  • Specimen Storage: Specimens should be stored at room temperature until ready for testing
  • Specimen Transport: Specimens should be shipped at room temperature
  • Clinical History: A detailed clinical history of the patient should be provided
  • Requisition Form: A completed requisition form with patient information, ordering physician information, and test requested

What are the measure values for the test PDGFR Alpha (4q12) Gene Rearrangement Test By FISH

  • Normal: No rearrangement of PDGFR Alpha gene detected
  • Abnormal: Rearrangement of PDGFR Alpha gene detected

What does this test PDGFR Alpha (4q12) Gene Rearrangement Test By FISH identify?

  • This test identifies rearrangements involving the PDGFR Alpha gene located on chromosome 4q12.
  • The PDGFR Alpha gene codes for a receptor tyrosine kinase involved in cell growth and differentiation.
  • Rearrangements in the PDGFR Alpha gene can lead to abnormal activation of the receptor, which may contribute to the development of certain cancers.
  • Fluorescence in situ hybridization (FISH) is a technique used to detect specific DNA sequences in cells, allowing for the identification of rearrangements involving the PDGFR Alpha gene.
  • Results of this test can help in the diagnosis and treatment of cancers associated with PDGFR Alpha gene rearrangements.

Why is this test PDGFR Alpha (4q12) Gene Rearrangement Test By FISH taken?

Test Name: PDGFR Alpha (4q12) Gene Rearrangement Test By FISH

Reason for Test:

  • To detect rearrangements involving the PDGFR Alpha gene located on chromosome 4q12
  • To diagnose certain types of cancer, such as myeloproliferative neoplasms
  • To guide treatment decisions, as certain rearrangements may indicate responsiveness to specific targeted therapies
  • To monitor disease progression and response to treatment

Popular FAQs on Test

The PDGFR Alpha (4q12) Gene Rearrangement Test By FISH is a molecular test that detects rearrangements involving the PDGFR Alpha gene on chromosome 4q12. This test is used to help diagnose certain types of leukemia and other blood disorders.
The PDGFR Alpha (4q12) Gene Rearrangement Test By FISH is performed to help diagnose and monitor certain types of leukemia and other blood disorders. It can also help guide treatment decisions and assess response to therapy.
The PDGFR Alpha (4q12) Gene Rearrangement Test By FISH is performed on a sample of blood or bone marrow cells. The cells are analyzed using a fluorescent in situ hybridization (FISH) technique to detect rearrangements involving the PDGFR Alpha gene.
The results of the PDGFR Alpha (4q12) Gene Rearrangement Test By FISH can help confirm a diagnosis of certain types of leukemia or other blood disorders. Positive results may indicate the presence of a PDGFR Alpha gene rearrangement, while negative results suggest the absence of such rearrangements.
The PDGFR Alpha (4q12) Gene Rearrangement Test By FISH is a minimally invasive procedure and is generally considered safe. However, as with any medical test, there is a small risk of infection, bleeding, or bruising at the site where the sample is taken.

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