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Reports Within:

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Requisites
Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days the report can be obtained for the Inv(3) (MECOM, 3q26) Gene Rearrangement Test By FISH is typically 14-21 days from the date of sample receipt in the laboratory.

What are the prerequisites for the test Inv(3) (MECOM, 3q26) Gene Rearrangement Test By FISH

  • Specimen Type: Bone marrow aspirate or peripheral blood
  • Specimen Container: Green top (sodium heparin) tube or yellow top (ACD) tube
  • Specimen Volume: 2-5 mL
  • Specimen Stability: Ambient: 24 hours; Refrigerated: 72 hours; Frozen: Unacceptable
  • Transport Temperature: Ambient or refrigerated
  • Methodology: Fluorescence in situ hybridization (FISH)
  • Turnaround Time: 5-7 days
  • Preferred Specimen: Bone marrow aspirate
  • Acceptable Specimen: Peripheral blood

What are the measure values for the test Inv(3) (MECOM, 3q26) Gene Rearrangement Test By FISH

  • Normal: 2 signals (2F2R)
  • Abnormal: 1 signal (1F1R)
  • Abnormal: 3 signals (3F3R)
  • Abnormal: Gene fusion

What does this test Inv(3) (MECOM, 3q26) Gene Rearrangement Test By FISH identify?

The Inv(3) (MECOM, 3q26) Gene Rearrangement Test By FISH identifies rearrangements involving the MECOM gene located on chromosome 3q26. This test uses Fluorescence In Situ Hybridization (FISH) to detect any abnormalities in the genetic material of this gene, which may be associated with certain hematologic malignancies such as acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). By analyzing the rearrangements of the MECOM gene, this test can help in the diagnosis and treatment of these types of cancers.

Why is this test Inv(3) (MECOM, 3q26) Gene Rearrangement Test By FISH taken?

Inv(3) (MECOM, 3q26) Gene Rearrangement Test By FISH

The Inv(3) (MECOM, 3q26) Gene Rearrangement Test By FISH is taken to detect any rearrangements or abnormalities in the MECOM gene located on chromosome 3q26. This test is important for the diagnosis and monitoring of certain types of leukemia, as well as other hematologic disorders.

Rearrangements in the MECOM gene can lead to the overexpression of the gene, which has been implicated in the development and progression of leukemia. By identifying these rearrangements through FISH (Fluorescence In Situ Hybridization) testing, healthcare providers can determine the best course of treatment for patients and monitor their response to therapy.

Overall, the Inv(3) (MECOM, 3q26) Gene Rearrangement Test By FISH plays a crucial role in the management of leukemia and other related conditions, helping to guide treatment decisions and improve patient outcomes.

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