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Number of red blood cells in the blood

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Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

Maximum Days for Obtaining MTHFR-2 Variants Test Report:

The maximum days for obtaining the report for the Methylenetetrahydrofolate Reductase (MTHFR)- 2 Variants (C677T, A1298C) Test is typically 5-7 business days from the date of sample collection.

What are the prerequisites for the test Methylenetetrahydrofolate Reductase (MTHFR)- 2 Variants (C677T, A1298C) Test

  • Patient must be fasting for at least 8 hours prior to the test
  • Inform the healthcare provider about any medications or supplements being taken
  • Provide a complete medical history, including any family history of genetic disorders
  • Discuss any symptoms or concerns related to folate metabolism or MTHFR gene mutations

What are the measure values for the test Methylenetetrahydrofolate Reductase (MTHFR)- 2 Variants (C677T, A1298C) Test

  • MTHFR C677T Variant: Normal = CC, Heterozygous = CT, Homozygous = TT
  • MTHFR A1298C Variant: Normal = AA, Heterozygous = AC, Homozygous = CC

What does this test Methylenetetrahydrofolate Reductase (MTHFR)- 2 Variants (C677T, A1298C) Test identify?

Methylenetetrahydrofolate Reductase (MTHFR)- 2 Variants (C677T, A1298C) Test

The Methylenetetrahydrofolate Reductase (MTHFR) test identifies two common variants in the MTHFR gene - C677T and A1298C. These variants can affect the activity of the MTHFR enzyme, which is involved in the metabolism of folate.

The C677T variant has been associated with reduced enzyme activity, leading to higher levels of homocysteine in the blood. Elevated homocysteine levels are a risk factor for cardiovascular disease and other health issues.

The A1298C variant is also associated with decreased enzyme activity, although its effects on homocysteine levels are less clear. Some studies suggest that this variant may be linked to certain neurological conditions.

Testing for these MTHFR variants can help identify individuals who may benefit from folate supplementation or other interventions to optimize their health. It can also provide valuable information for healthcare providers in managing patients with conditions related to MTHFR gene variants.

Why is this test Methylenetetrahydrofolate Reductase (MTHFR)- 2 Variants (C677T, A1298C) Test taken?

The Methylenetetrahydrofolate Reductase (MTHFR) - 2 Variants (C677T, A1298C) Test is taken to detect genetic variations in the MTHFR gene. The MTHFR gene provides instructions for making an enzyme called methylenetetrahydrofolate reductase, which plays a key role in processing amino acids for protein synthesis and in converting homocysteine to methionine.

Variations in the MTHFR gene, specifically the C677T and A1298C variants, can lead to reduced enzyme activity and impaired function. These variations have been associated with an increased risk of conditions such as cardiovascular disease, neural tube defects, and pregnancy complications.

By identifying these genetic variants through the MTHFR - 2 Variants Test, healthcare providers can assess an individual's risk for certain health conditions and develop personalized treatment plans to manage or prevent these conditions.

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