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Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

Maximum Days for E-Cadherin (ECAD) Test Immunohistochemistry Report:

The maximum days for obtaining the report of the E-Cadherin (ECAD) Test Immunohistochemistry is 7 days.

What are the prerequisites for the test E-Cadherin (ECAD) Test Immunohistochemistry

  • Formalin-fixed, paraffin-embedded tissue samples
  • Deparaffinized and rehydrated tissue sections on slides
  • Antigen retrieval solution (e.g. citrate buffer)
  • Blocking solution (e.g. normal serum)
  • Primary antibody against E-Cadherin (ECAD)
  • Secondary antibody conjugated with a detection system (e.g. HRP)
  • Visualization system (e.g. DAB substrate)
  • Mounting medium for microscopy analysis

What are the measure values for the test E-Cadherin (ECAD) Test Immunohistochemistry

Measure Value
Positive Strong membrane staining in >70% of tumor cells
Weak Positive Weak membrane staining in 30-70% of tumor cells
Negative No staining or weak staining in <30% of tumor cells

What does this test E-Cadherin (ECAD) Test Immunohistochemistry identify?

E-Cadherin (ECAD) Test Immunohistochemistry

The E-Cadherin (ECAD) Test Immunohistochemistry is a diagnostic test that identifies the presence of E-Cadherin protein in tissues. E-Cadherin is a cell adhesion molecule that plays a crucial role in maintaining the integrity of epithelial tissues by mediating cell-cell adhesion.

Abnormal expression or loss of E-Cadherin protein has been associated with various cancers, particularly in epithelial tumors such as breast, gastric, and colorectal cancers. Therefore, the ECAD test helps in the diagnosis and prognosis of these cancers by assessing the level of E-Cadherin expression in tissue samples.

Why is this test E-Cadherin (ECAD) Test Immunohistochemistry taken?

Reasons for E-Cadherin (ECAD) Test Immunohistochemistry:

The E-Cadherin (ECAD) Test Immunohistochemistry is taken for the following reasons:

  • Assessment of tumor metastasis: E-Cadherin is a protein involved in cell-cell adhesion, and its expression can impact the ability of tumor cells to metastasize. Testing for E-Cadherin levels can help in predicting the metastatic potential of a tumor.
  • Determination of tumor aggressiveness: Low levels of E-Cadherin have been associated with more aggressive tumors. By measuring E-Cadherin expression, healthcare providers can assess the aggressiveness of a tumor and tailor treatment accordingly.
  • Diagnosis of certain cancers: Changes in E-Cadherin expression levels have been observed in various types of cancers, including breast, prostate, and gastric cancers. The ECAD test can aid in the diagnosis of these cancers.
  • Monitoring treatment response: E-Cadherin levels may change in response to certain cancer treatments. Regular monitoring of E-Cadherin expression can help in evaluating the effectiveness of the treatment and making necessary adjustments.

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