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Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days the report can be obtained for the Isocitrate Dehydrogenase (IDH-1) Test Immunohistochemistry is typically 7-10 business days. However, this may vary depending on the laboratory or healthcare provider conducting the test.

What are the prerequisites for the test Isocitrate Dehydrogenase (IDH-1) Test Immunohistochemistry

  • Formalin-fixed, paraffin-embedded tissue block or unstained slides
  • Specimen should be received within 48 hours of collection
  • Requisition form with patient information and clinical history
  • Properly completed test request form

What are the measure values for the test Isocitrate Dehydrogenase (IDH-1) Test Immunohistochemistry

  • Positive: Strong cytoplasmic staining in tumor cells
  • Negative: Absence of staining in tumor cells
  • Intensity: 0 (no staining), 1+ (weak staining), 2+ (moderate staining), 3+ (strong staining)
  • Percentage of stained cells: 0-100%

What does this test Isocitrate Dehydrogenase (IDH-1) Test Immunohistochemistry identify?

Isocitrate Dehydrogenase (IDH-1) Test Immunohistochemistry

The Isocitrate Dehydrogenase (IDH-1) Test Immunohistochemistry is a diagnostic test used to identify mutations in the IDH-1 gene in tissue samples. This test is commonly used in the diagnosis and prognosis of certain types of brain tumors, such as gliomas and astrocytomas.

The IDH-1 gene encodes for the enzyme isocitrate dehydrogenase, which plays a crucial role in cellular metabolism. Mutations in the IDH-1 gene have been found to be associated with certain types of cancer, including brain tumors. In particular, mutations in the IDH-1 gene result in the production of a mutant protein that can drive tumorigenesis and influence patient outcomes.

By performing immunohistochemistry on tissue samples, pathologists can determine if there is an overexpression of the mutant IDH-1 protein, which can help in the diagnosis and classification of brain tumors. This information is valuable in guiding treatment decisions and predicting patient outcomes.

Why is this test Isocitrate Dehydrogenase (IDH-1) Test Immunohistochemistry taken?

Isocitrate Dehydrogenase (IDH-1) Test Immunohistochemistry

The Isocitrate Dehydrogenase (IDH-1) Test Immunohistochemistry is taken to detect the presence of mutations in the IDH-1 gene. Mutations in this gene are commonly found in certain types of cancers, including brain tumors such as gliomas and acute myeloid leukemia.

By performing this test, healthcare providers can determine if a patient's tumor carries the IDH-1 mutation, which can help in diagnosing the type of cancer and guiding treatment decisions. This test is typically done on tissue samples obtained from a biopsy or surgical resection of the tumor.

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