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Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

Test Name Epidermal Growth Factor Receptor (EGFR) Test Immunohistochemistry
Maximum Days for Report Usually 7-10 business days

What are the prerequisites for the test Epidermal Growth Factor Receptor (EGFR) Test Immunohistochemistry

  • Formalin-fixed, paraffin-embedded tissue sample
  • Properly labeled tissue slides
  • Positive and negative control tissues
  • Antibodies specific for EGFR
  • Antigen retrieval solution
  • Biotinylated secondary antibodies
  • Streptavidin-biotin complex
  • Chromogen substrate
  • Counterstain solution
  • Microscope for analysis

What are the measure values for the test Epidermal Growth Factor Receptor (EGFR) Test Immunohistochemistry

  • Positive: Strong membranous staining in >50% of tumor cells
  • Equivoval: Weak to moderate membranous staining in <50% of tumor cells
  • Negative: Absence of membranous staining in tumor cells

What does this test Epidermal Growth Factor Receptor (EGFR) Test Immunohistochemistry identify?

Epidermal Growth Factor Receptor (EGFR) Test Immunohistochemistry
This test identifies the presence of Epidermal Growth Factor Receptor (EGFR) protein in tissue samples. EGFR is a cell surface receptor that plays a crucial role in cell growth and division. Abnormalities in EGFR expression have been linked to various cancers, particularly lung cancer. Immunohistochemistry is a method that uses antibodies to detect specific proteins in tissue samples, allowing for the identification and localization of EGFR protein in cancer cells. This test helps in determining the EGFR status of a tumor, which can guide treatment decisions, such as the use of targeted therapies that block EGFR signaling.

Why is this test Epidermal Growth Factor Receptor (EGFR) Test Immunohistochemistry taken?

The Epidermal Growth Factor Receptor (EGFR) Test Immunohistochemistry is taken to determine the presence and amount of EGFR protein on the surface of cancer cells. EGFR is a protein that is involved in cell growth and division, and overexpression of EGFR has been linked to certain types of cancer, particularly lung cancer.

By performing the EGFR Test Immunohistochemistry, doctors can assess the expression of EGFR in a tissue sample taken from a tumor. This information can help in determining the prognosis of the cancer, as well as guiding treatment decisions. For example, some cancer treatments specifically target the EGFR protein, so knowing the EGFR status of a tumor can help in selecting the most effective treatment for a patient.

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