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Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days for obtaining the report for the MDM2 Test Immunohistochemistry is 5-7 business days.

What are the prerequisites for the test MDM2 Test Immunohistochemistry

  • Formalin-fixed, paraffin-embedded tissue block or slides
  • Specimen should be fixed in 10% neutral buffered formalin for 6-48 hours
  • Specimen should be processed and embedded in paraffin within 48 hours of fixation
  • Tissue sections should be cut at 4-5 microns thickness
  • Slides should be positively charged
  • Proper controls should be included in the staining protocol

What are the measure values for the test MDM2 Test Immunohistochemistry

  • Positive: Strong nuclear staining in more than 50% of tumor cells
  • Weak Positive: Weak nuclear staining in less than 50% of tumor cells
  • Negative: No nuclear staining or faint staining in less than 10% of tumor cells

What does this test MDM2 Test Immunohistochemistry identify?

  • MDM2 Test Immunohistochemistry identifies the expression levels of the MDM2 protein in a tissue sample.
  • MDM2 is a key regulator of the p53 tumor suppressor protein and is often overexpressed in various types of cancer.
  • High levels of MDM2 protein expression can indicate the presence of certain types of cancer, such as sarcoma or liposarcoma.
  • The test involves using specific antibodies to detect MDM2 protein in the tissue sample, typically through immunohistochemical staining techniques.
  • Results of the MDM2 Test Immunohistochemistry can help in diagnosing and guiding treatment decisions for cancer patients.

Why is this test MDM2 Test Immunohistochemistry taken?

The MDM2 Test Immunohistochemistry is taken to detect the overexpression of MDM2 protein in tissue samples. MDM2 is a key regulator of the p53 tumor suppressor gene and plays a role in cell growth and proliferation. Overexpression of MDM2 can lead to inactivation of p53 and promote tumor growth. This test is commonly used in the diagnosis and prognosis of various cancers, including soft tissue sarcomas and some types of lymphomas. The results of the test can help guide treatment decisions and predict patient outcomes.

Popular FAQs on Test

MDM2 Test Immunohistochemistry is a test used to detect the overexpression of MDM2 protein in tumor cells. MDM2 is a protein that helps regulate the activity of the tumor suppressor gene p53. Overexpression of MDM2 can lead to inactivation of p53 and promote tumor growth.
MDM2 Test Immunohistochemistry is performed to aid in the diagnosis of certain types of cancers, such as liposarcoma and dedifferentiated chondrosarcoma. It can also help determine the prognosis of these cancers and guide treatment decisions.
MDM2 Test Immunohistochemistry is performed on a tissue sample obtained from a biopsy or surgical resection. The tissue sample is stained with antibodies that specifically target the MDM2 protein. The presence and level of MDM2 protein expression in the tumor cells are then examined under a microscope.
The possible results of MDM2 Test Immunohistochemistry include positive staining, indicating overexpression of MDM2 protein in tumor cells, and negative staining, indicating normal levels of MDM2 protein. Positive staining may suggest a diagnosis of liposarcoma or dedifferentiated chondrosarcoma.
While MDM2 Test Immunohistochemistry is a valuable tool in the diagnosis and prognosis of certain cancers, it is not 100% accurate. False-positive and false-negative results can occur, and additional testing may be needed to confirm a diagnosis.

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